Autoimmune

Autoimmune (Broad)
Shopping & Supplement List

Root cause chain: Gut permeability → immune trigger unresolved → antibodies attack own tissue → systemic inflammation → organ involvement

Every item is selected for its specific role in the biological chain driving this condition. This is not a generic health food list.

✓ Foods to prioritise
Wild-caught fatty fish
Omega-3 EPA and DHA reduce the Th17 inflammatory response driving autoimmune tissue damage.
Bone broth
Collagen, glycine, and proline repair the gut lining — the upstream driver of most autoimmune conditions.
Sweet potato and cassava (AIP compliant)
Starchy carbohydrates that feed beneficial bacteria without nightshade immune triggers.
Coconut oil and avocado
Anti-inflammatory fats that support T-regulatory cell function. Coconut contains lauric acid with immune-modulating properties.
Leafy greens — cooked
Folate and magnesium support methylation — the process that regulates inflammatory gene expression. Cooked reduces oxalate load.
Turmeric in cooking
Daily curcumin exposure through food maintains NF-kB suppression between supplement doses.
Organ meats (if tolerated)
Nutrient-dense source of vitamin A, D, B12, and copper — all required for immune regulation and cannot be matched by plant sources.
Berries
Polyphenols specifically reduce the Th17/Th1 imbalance driving autoimmune inflammation.
✕ Foods to eliminate or reduce
Grains including gluten-free grains
During AIP phase — all grains can trigger immune activation through lectin and phytate mechanisms.
Nightshades (AIP phase)
Tomatoes, peppers, aubergine, potatoes — contain alkaloids that increase gut permeability and trigger immune activation.
Dairy
Casein proteins trigger immune cross-reactivity in many autoimmune conditions. Eliminate during active antibody phase.
Legumes
Lectins and phytates disrupt gut lining integrity. Eliminate during AIP phase.
Seed oils
Omega-6 dominant — directly amplify the Th17 inflammatory pathway driving autoimmune tissue damage.
Alcohol
Activates NF-kB, increases gut permeability, and suppresses T-regulatory cells simultaneously.
⚗ Supplement protocol
Vitamin D3 + K2
Primary immune modulator. Shifts from Th17 (autoimmune) to T-regulatory (calming). Non-negotiable.
5000 IU D3 + 100mcg K2 daily
Omega-3 (EPA/DHA)
Therapeutic anti-inflammatory dose. Reduces IL-6, TNF-alpha, and prostaglandin production.
2-3g EPA/DHA daily with food
Curcumin with Piperine
NF-kB inhibitor — the master inflammatory switch. BCM-95 or Theracurmin for best absorption.
500-1000mg twice daily with food
Low-dose Melatonin
Immune modulator and oncostatic. Enhances NK cell activity and T-regulatory cell function.
0.5-1mg before sleep
Magnesium Glycinate
Anti-inflammatory, reduces cortisol, improves sleep architecture.
400mg evening
L-Glutamine
Repairs gut lining — the upstream driver of most autoimmune triggers.
5g morning on empty stomach
Probiotics — multi-strain
Restores microbiome diversity. Reduces autoimmune activation through GALT modulation.
50 billion CFU multi-strain daily

Supplements without a root cause map
are expensive guesswork.

This list addresses the known drivers of Autoimmune (Broad). A root cause conversation identifies which specific markers are active in your case — and which interventions are most relevant to your biology specifically.

Book Your Free Root Cause Call
Not a sales call. A root cause conversation. You will leave with clarity regardless.
⚕️
Medical Disclaimer: These protocols are based on patterns observed across clinical cases and are provided for general educational purposes only. They are not medical advice, not a substitute for professional diagnosis or treatment, and should not replace guidance from a qualified healthcare practitioner. Every individual is biochemically unique — what works for one person may not be appropriate for another. If you have a diagnosed condition or are on medication, consult your practitioner before making changes.