Magnesium Glycinate
Natural GABA activator. Most studied mineral for anxiety reduction. Deficiency is the most common nutritional driver.
200mg morning + 400mg evening
Ashwagandha (KSM-66)
Directly reduces serum cortisol. Significant anxiety reduction in clinical trials within 8 weeks.
300mg twice daily with food
L-Theanine
Increases alpha brain waves without sedation. Modulates GABA and glutamate. Safe long-term.
200mg as needed, or with caffeine
GABA (PharmaGABA)
Natural form crosses blood-brain barrier. Direct inhibitory neurotransmitter effect. Most effective for physical tension component.
100-200mg before sleep or stressful events
B Complex (methylated)
B6 is required for GABA synthesis. B12 and folate for serotonin production. Methylated forms bypass MTHFR issues.
Daily with breakfast
Probiotics — multi-strain
Restores gut bacteria producing serotonin and GABA. Gut-brain axis upstream fix for biological anxiety.
50 billion CFU multi-strain daily
Rhodiola Rosea
Adaptogen that improves stress resilience and reduces cortisol response. Does not cause sedation.
300-400mg morning